Genetic heterogeneity of primary open angle glaucoma and ocular hypertension: linkage to GLC1A associated with an increased risk of severe glaucomatous optic neuropathy.

The GLC1A locus for autosomal dominant juvenile and middle age onset primary open angle glaucoma (OAG) has been mapped to chromosome 1q21-q31. OAG, however, is a heterogeneous disease. We tested linkage of OAG and ocular hypertension (OHT), a major risk factor for OAG, to GLC1A in eight French famil...

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Detalhes bibliográficos
Main Authors: Brézin, A P, Béchetoille, A, Hamard, P, Valtot, F, Berkani, M, Belmouden, A, Adam, M F, Dupont de Dinechin, S, Bach, J F, Garchon, H J
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1050993/
https://ncbi.nlm.nih.gov/pubmed/9222961
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