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A variant of the Nijmegen breakage syndrome with unusual cytogenetic features and intermediate cellular radiosensitivity.

We report the first Italian case of Nijmegen breakage syndrome (NBS). The proband is an immunodeficient, microcephalic, 11 year old boy with a "bird-like" face. He developed a T cell rich B cell lymphoma. Spontaneous chromosomal instability was detected in T and B lymphocytes and fibroblas...

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Detalhes bibliográficos
Main Authors: Tupler, R, Marseglia, G L, Stefanini, M, Prosperi, E, Chessa, L, Nardo, T, Marchi, A, Maraschio, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1050892/
https://ncbi.nlm.nih.gov/pubmed/9132489
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