Linkage of rheumatoid arthritis to the candidate gene NRAMP1 on 2q35.

The macrophage resistance gene NRAMP1 regulates priming/activation of macrophages for enhanced TNF alpha, IL 1 beta, and MHC class II expression. Since all of these functions are of potential importance in the induction or maintenance or both of autoimmune disease, samples from the Arthritis and Rhe...

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Autors principals: Shaw, M A, Clayton, D, Atkinson, S E, Williams, H, Miller, N, Sibthorpe, D, Blackwell, J M
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1050702/
https://ncbi.nlm.nih.gov/pubmed/8863160
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