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Large scale deletions of the 5q13 region are specific to Werdnig-Hoffmann disease.

Spinal muscular atrophy (SMA) is characterised by degeneration of anterior horn cells of the spinal cord and represents the second most common, lethal, autosomal recessive disorder after cystic fibrosis. Based on the criteria of the Internatinal SMA Consortium, childhood SMAs are classified into typ...

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Detalhes bibliográficos
Main Authors: Burlet, P, Bürglen, L, Clermont, O, Lefebvre, S, Viollet, L, Munnich, A, Melki, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1050575/
https://ncbi.nlm.nih.gov/pubmed/8730281
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