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Haplotype associations of three DNA polymorphisms at the human low density lipoprotein receptor gene locus in familial hypercholesterolaemia.

The frequency and inheritance of three restriction fragment length polymorphisms (RFLPs) of the low density lipoprotein (LDL) receptor gene were investigated in 27 South African families with familial hypercholesterolaemia. Four haplotypes, defined by the enzymes PvuII, StuI, and NcoI, were found to...

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Dettagli Bibliografici
Autori principali: Kotze, M J, Langenhoven, E, Retief, A E, Steyn, K, Marais, M P, Grobbelaar, J J, Oosthuizen, C J, Weich, H F, Benadé, A J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1987
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1050403/
https://ncbi.nlm.nih.gov/pubmed/3430554
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