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A model system for the analysis of gene exclusion: cystic fibrosis and chromosome 19.

We have used multilocus analysis to exclude the cystic fibrosis locus from six polymorphic DNA markers covering most of chromosome 19. A substantial increase in the confidence for exclusion was obtained using the computer programme LINKAGE compared to analysis of pairwise lod scores. A structured ap...

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Main Authors: Wainwright, B, Farrall, M, Watson, E, Williamson, R
Formato: Artigo
Idioma:Inglês
Publicado: 1986
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1049778/
https://ncbi.nlm.nih.gov/pubmed/3783618
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