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Gene deletion in an Italian haemophilia B subject.

DNA from 20 Italian haemophilia B patients was analysed by the Southern blotting technique and hybridisation to a factor IX cDNA probe. A large deletion of factor IX gene was detected in one patient with antibodies to the infused factor; the EcoRI pattern of the other 19 subjects examined was normal...

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Detalhes bibliográficos
Main Authors: Bernardi, F, del Senno, L, Barbieri, R, Buzzoni, D, Gambari, R, Marchetti, G, Conconi, F, Panicucci, F, Positano, M, Pitruzzello, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1049455/
https://ncbi.nlm.nih.gov/pubmed/4045960
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