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The cause of neural tube defects: some experiments and a hypothesis.

The mouse mutant curly-tail is an animal model for human neural tube defects (NTD). Around 60% spontaneously have NTD. It has been found that maternal administration of hydroxyurea, mitomycin C, or 5-fluorouracil on day 9 of pregnancy, that is, when the fetal neural tube is in the final stages of cl...

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Autor principal: Seller, M J
Format: Artigo
Idioma:Inglês
Publicat: 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1049040/
https://ncbi.nlm.nih.gov/pubmed/6876107
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