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The mutation rate to Huntington's chorea

The problems of estimating the mutation rate to Huntington's chorea, or the proportion of new mutants among all sufferers, are discussed. The available survey data are reviewed. The prevalence of sporadic phenotypes, which include new mutations, is probably less than 2·5%. New mutants probably...

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Bibliografske podrobnosti
Main Authors: Shaw, Michael, Caro, Adrian
Format: Artigo
Jezik:Inglês
Izdano: 1982
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1048861/
https://ncbi.nlm.nih.gov/pubmed/6213773
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