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The mutation rate to Huntington's chorea

The problems of estimating the mutation rate to Huntington's chorea, or the proportion of new mutants among all sufferers, are discussed. The available survey data are reviewed. The prevalence of sporadic phenotypes, which include new mutations, is probably less than 2·5%. New mutants probably...

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Detalles Bibliográficos
Main Authors: Shaw, Michael, Caro, Adrian
Formato: Artigo
Idioma:Inglês
Publicado: 1982
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1048861/
https://ncbi.nlm.nih.gov/pubmed/6213773
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