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Use of 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyl Tetrazolium Bromide for Rapid Detection of Rifampin-Resistant Mycobacterium tuberculosis

We describe a test which uses the ability of viable cells to reduce 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) to detect resistance to a bactericidal drug, rifampin, in in vitro-cultured Mycobacterium tuberculosis. The assay shows a linear relationship between the number of...

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Udgivet i:J Clin Microbiol
Principais autores: Mshana, Robert N., Tadesse, Genet, Abate, Getahun, Miörner, Håkan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Mycobacteriology and Aerobic Actinomycetes
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104802/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9574679/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.36.5.1214-1219.1998
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