Diversity of Helicobacter pylori vacA and cagA Genes and Relationship to VacA and CagA Protein Expression, Cytotoxin Production, and Associated Diseases

The vacuolating cytotoxin and the cytotoxin-associated protein, encoded by vacA and cagA, respectively, are important virulence determinants of Helicobacter pylori. Sixty-five H. pylori strains were isolated from dyspeptic patients (19 with peptic ulcer disease, 43 with chronic gastritis, and 3 with...

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Bibliographic Details
Main Authors: Rudi, Jochen, Kolb, Christof, Maiwald, Matthias, Kuck, Dirk, Sieg, Andreas, Galle, Peter R., Stremmel, Wolfgang
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Bacteriology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC104665/
https://ncbi.nlm.nih.gov/pubmed/9542913
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