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The Tumor Necrosis Factor-Inducing Potency of Lipopolysaccharide and Uronic Acid Polymers Is Increased when They Are Covalently Linked to Particles

Lipopolysaccharide (LPS) and polymers of the uronic acid family stimulate monocytes to produce tumor necrosis factor (TNF). The TNF-inducing potency of these polysaccharides may depend on their supramolecular configuration. In this study detoxified LPS and uronic acid polymers have been covalently l...

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Autors principals: Berntzen, Gøril, Flo, Trude H., Medvedev, Andrei, Kilaas, Lars, Skjåk-Bræk, Gudmund, Sundan, Anders, Espevik, Terje
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC104524/
https://ncbi.nlm.nih.gov/pubmed/9605991
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