Human Immunodeficiency Virus Type 1 Integrase Protein Promotes Reverse Transcription through Specific Interactions with the Nucleoprotein Reverse Transcription Complex

The human immunodeficiency virus type 1 (HIV-1) integrase protein (IN) is essential for integration of the viral DNA into host cell chromosomes. Since IN is expressed and assembled into virions as part of the 160-kDa Gag-Pol precursor polyprotein and catalyzes integration of the provirus in infected...

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Autores principales: Wu, Xiaoyun, Liu, Hongmei, Xiao, Hongling, Conway, Joan A., Hehl, Eric, Kalpana, Ganjam V., Prasad, Vinayaka, Kappes, John C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
Materias:
Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC104457/
https://ncbi.nlm.nih.gov/pubmed/9971795
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