Human Immunodeficiency Virus Type 1 Integrase Protein Promotes Reverse Transcription through Specific Interactions with the Nucleoprotein Reverse Transcription Complex

The human immunodeficiency virus type 1 (HIV-1) integrase protein (IN) is essential for integration of the viral DNA into host cell chromosomes. Since IN is expressed and assembled into virions as part of the 160-kDa Gag-Pol precursor polyprotein and catalyzes integration of the provirus in infected...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Wu, Xiaoyun, Liu, Hongmei, Xiao, Hongling, Conway, Joan A., Hehl, Eric, Kalpana, Ganjam V., Prasad, Vinayaka, Kappes, John C.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1999
Assuntos:	Replication
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104457/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9971795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.3.2126-2135.1999
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