Open Reading Frame 1a-Encoded Subunits of the Arterivirus Replicase Induce Endoplasmic Reticulum-Derived Double-Membrane Vesicles Which Carry the Viral Replication Complex

The replicase of equine arteritis virus (EAV; family Arteriviridae, order Nidovirales) is expressed in the form of two polyproteins (the open reading frame 1a [ORF1a] and ORF1ab proteins). Three viral proteases cleave these precursors into 12 nonstructural proteins, which direct both genome replicat...

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Hlavní autoři: Pedersen, Ketil W., van der Meer, Yvonne, Roos, Norbert, Snijder, Eric J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC104444/
https://ncbi.nlm.nih.gov/pubmed/9971782
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