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Regulatory Role of the Conserved Stem-Loop Structure at the 5′ End of Collagen α1(I) mRNA

Three fibrillar collagen mRNAs, α1(I), α2(I), and α1(III), are coordinately upregulated in the activated hepatic stellate cell (hsc) in liver fibrosis. These three mRNAs contain sequences surrounding the start codon that can be folded into a stem-loop structure. We investigated the role of this stem...

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Hlavní autoři: Stefanovic, B., Hellerbrand, C., Brenner, D. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC104393/
https://ncbi.nlm.nih.gov/pubmed/10330174
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