Role of Phosphoinositide 3-Kinase in Activation of Ras and Mitogen-Activated Protein Kinase by Epidermal Growth Factor

The paradigm for activation of Ras and extracellular signal-regulated kinase (ERK)/mitogen-activated protein (MAP) kinase by extracellular stimuli via tyrosine kinases, Shc, Grb2, and Sos does not encompass an obvious role for phosphoinositide (PI) 3-kinase, and yet inhibitors of this lipid kinase f...

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Bibliografische gegevens

Gepubliceerd in:	Mol Cell Biol
Hoofdauteurs:	Wennström, Stefan, Downward, Julian
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Taylor & Francis 1999
Onderwerpen:	Cell Growth and Development
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10330169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.6.4279
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