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Both Transcriptional and Posttranscriptional Mechanisms Regulate Human Telomerase Template RNA Levels

The human telomerase RNA component (hTR) is present in normal somatic cells at lower levels than in cancer-derived cell lines. To understand the mechanisms regulating hTR levels in different cell types, we have compared the steady-state hTR levels in three groups of cells: (i) normal telomerase-nega...

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Autores principales: Yi, Xiaoming, Tesmer, Valerie M., Savre-Train, Isabelle, Shay, Jerry W., Wright, Woodring E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC104358/
https://ncbi.nlm.nih.gov/pubmed/10330139
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