Both Transcriptional and Posttranscriptional Mechanisms Regulate Human Telomerase Template RNA Levels

The human telomerase RNA component (hTR) is present in normal somatic cells at lower levels than in cancer-derived cell lines. To understand the mechanisms regulating hTR levels in different cell types, we have compared the steady-state hTR levels in three groups of cells: (i) normal telomerase-nega...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Yi, Xiaoming, Tesmer, Valerie M., Savre-Train, Isabelle, Shay, Jerry W., Wright, Woodring E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1999
Soggetti:	Gene Expression
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104358/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10330139/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.6.3989
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