Expanded Tropism of Primary Human Immunodeficiency Virus Type 1 R5 Strains to CD4(+) T-Cell Lines Determined by the Capacity To Exploit Low Concentrations of CCR5

Human immunodeficiency virus type 1 (HIV-1) non-syncytium-inducing (NSI) strains predominantly use the chemokine receptor CCR5, while syncytium-inducing (SI) strains use CXCR4. In vitro, SI isolates infect and replicate in a range of CD4(+) CXCR4(+) T-cell lines, whereas NSI isolates usually do not....

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Dejucq, Nathalie, Simmons, Graham, Clapham, Paul R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7842-7847.1999
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