The E7 Oncoprotein of Human Papillomavirus Type 16 Stabilizes p53 through a Mechanism Independent of p19(ARF)

High-risk human papillomaviruses are causally associated with cervical cancer. Two viral oncogenes, E6 and E7, are expressed in most cervical cancers, and these genes cause cancer when expressed in experimental animals. The E6 protein targets the p53 tumor suppressor for degradation, while the E7 pr...

Descrición completa

Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Seavey, Scott E., Holubar, Marisa, Saucedo, Leslie J., Perry, Mary Ellen
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1999
Assuntos:	Transformation and Oncogenesis
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104286/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438849/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7590-7598.1999
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!