High-Fidelity Correction of Mutations at Multiple Chromosomal Positions by Adeno-Associated Virus Vectors

The gene targeting techniques used to modify chromosomes in mouse embryonic stem cells have had limited success with many other cell types, especially normal primary cells with restricted growth capacity outside the organism. This is due in large part to the technical problems and/or inefficiency of...

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Bibliographic Details
Main Authors: Inoue, Naoki, Hirata, Roli K., Russell, David W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Gene Therapy
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC104264/
https://ncbi.nlm.nih.gov/pubmed/10438827
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