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Moloney Murine Sarcoma Virus Genomic RNAs Dimerize via a Two-Step Process: a Concentration-Dependent Kissing-Loop Interaction Is Driven by Initial Contact between Consecutive Guanines

Retroviruses contain two plus-strand genomic RNAs, which are stably but noncovalently joined in their 5′ regions by a dimer linkage structure (DLS). Two models have been put forward to explain the mechanisms by which the RNAs dimerize; each model emphasizes the role of specific molecular determinant...

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Udgivet i:J Virol
Principais autores: Ly, Hinh, Nierlich, Donald P., Olsen, John C., Kaplan, Andrew H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Structure and Assembly
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104250/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438813/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7255-7261.1999
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