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The Presence of Human Immunodeficiency Virus Type 1 Vpr Correlates with a Decrease in the Frequency of Mutations in a Plasmid Shuttle Vector

The human immunodeficiency virus type 1 (HIV-1) Vpr protein induces cell cycle arrest at the border of G(2) and M similar to the arrest caused by agents which damage DNA. We determined whether the presence of Vpr would affect the ability of cells to repair DNA. We developed a shuttle vector system t...

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Udgivet i:J Virol
Principais autores: Jowett, Jeremy B., Xie, Yi-ming, Chen, Irvin S. Y.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104236/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438799/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7132-7137.1999
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