Role of CXCR4 in Cell-Cell Fusion and Infection of Monocyte-Derived Macrophages by Primary Human Immunodeficiency Virus Type 1 (HIV-1) Strains: Two Distinct Mechanisms of HIV-1 Dual Tropism

Dual-tropic human immunodeficiency virus type 1 (HIV-1) strains infect both primary macrophages and transformed T-cell lines. Prototype T-cell line-tropic (T-tropic) strains use CXCR4 as their principal entry coreceptor (X4 strains), while macrophagetropic (M-tropic) strains use CCR5 (R5 strains). P...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Yi, Yanjie, Isaacs, Stuart N., Williams, Darlisha A., Frank, Ian, Schols, Dominique, De Clercq, Erik, Kolson, Dennis L., Collman, Ronald G.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1999
Matèries:	Virus-Cell Interactions
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104231/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438797/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7117-7125.1999
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