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The Cholesterol Requirement for Sindbis Virus Entry and Exit and Characterization of a Spike Protein Region Involved in Cholesterol Dependence

Semliki Forest virus (SFV) and Sindbis virus (SIN) are enveloped alphaviruses that enter cells via low-pH-triggered fusion in the endocytic pathway and exit by budding from the plasma membrane. Previous studies with cholesterol-depleted insect cells have shown that SFV requires cholesterol in the ce...

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Autors principals: Lu, Yanping E., Cassese, Todd, Kielian, Margaret
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC104207/
https://ncbi.nlm.nih.gov/pubmed/10196324
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