Assembly of the Herpes Simplex Virus Procapsid from Purified Components and Identification of Small Complexes Containing the Major Capsid and Scaffolding Proteins

An in vitro system is described for the assembly of herpes simplex virus type 1 (HSV-1) procapsids beginning with three purified components, the major capsid protein (VP5), the triplexes (VP19C plus VP23), and a hybrid scaffolding protein. Each component was purified from insect cells expressing the...

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Autors principals: Newcomb, William W., Homa, Fred L., Thomsen, Darrell R., Trus, Benes L., Cheng, Naiqian, Steven, Alasdair, Booy, Frank, Brown, Jay C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Structure and Assembly
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC104203/
https://ncbi.nlm.nih.gov/pubmed/10196320
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