Nef Enhances Human Immunodeficiency Virus Replication and Responsiveness to Interleukin-2 in Human Lymphoid Tissue Ex Vivo

The nef gene is important for the pathogenicity associated with simian immunodeficiency virus infection in rhesus monkeys and with human immunodeficiency virus type 1 (HIV-1) infection in humans. The mechanisms by which nef contributes to pathogenesis in vivo remain unclear. We investigated the cont...

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Bibliographic Details
Main Authors: Glushakova, Svetlana, Grivel, Jean-Charles, Suryanarayana, Kalachar, Meylan, Pascal, Lifson, Jeffrey D., Desrosiers, Ronald, Margolis, Leonid
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC104175/
https://ncbi.nlm.nih.gov/pubmed/10196292
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