Replicative Fitness of Protease Inhibitor-Resistant Mutants of Human Immunodeficiency Virus Type 1

The relative replicative fitness of human immunodeficiency virus type 1 (HIV-1) mutants selected by different protease inhibitors (PIs) in vivo was determined. Each mutant was compared to wild type (WT), NL4-3, in the absence of drugs by several methods, including clonal genotyping of cultures infec...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Martinez-Picado, Javier, Savara, Anu V., Sutton, Lorraine, D’Aquila, Richard T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10196268/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.5.3744-3752.1999
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