Prevalent Class I-Restricted T-Cell Response to the Theiler’s Virus Epitope D(b):VP2(121–130) in the Absence of Endogenous CD4 Help, Tumor Necrosis Factor Alpha, Gamma Interferon, Perforin, or Costimulation through CD28

C57BL/6 mice mount a cytotoxic T-lymphocyte (CTL) response against the Daniel’s strain of Theiler’s murine encephalomyelitis virus (TMEV) 7 days after infection and do not develop persistent infection or the demyelinating syndrome similar to multiple sclerosis seen in susceptible mice. The TMEV caps...

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Main Authors: Johnson, Aaron J., Njenga, M. Kariuki, Hansen, Michael J., Kuhns, Scott T., Chen, Lieping, Rodriguez, Moses, Pease, Larry R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104145/
https://ncbi.nlm.nih.gov/pubmed/10196262
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