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Enrichment of a Precore-Minus Mutant of Duck Hepatitis B Virus in Experimental Mixed Infections

A precore-deficient mutant of duck hepatitis B virus (DHBV) produced by site-directed mutagenesis was tested for its ability to compete with wild-type virus in a mixed infection of 3-day-old ducklings. The mutation was shown to produce a cis-acting defect, resulting in a replication rate that was ab...

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Bibliografiske detaljer
Main Authors: Zhang, Yong-Yuan, Summers, Jesse
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC104136/
https://ncbi.nlm.nih.gov/pubmed/10196253
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