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Eukaryotic Initiation Factor 4GII (eIF4GII), but Not eIF4GI, Cleavage Correlates with Inhibition of Host Cell Protein Synthesis after Human Rhinovirus Infection

For many members of the Picornaviridae family, infection of cells results in a shutoff of host protein synthesis. For rhinoviruses and enteroviruses, the shutoff has been explained in part by the cleavage of eukaryotic initiation factor 4GI (eIF4GI), a component of the cap-binding protein complex eI...

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Detalhes bibliográficos
Main Authors: Svitkin, Yuri V., Gradi, Alessandra, Imataka, Hiroaki, Morino, Shigenobu, Sonenberg, Nahum
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104114/
https://ncbi.nlm.nih.gov/pubmed/10074204
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