The Bovine Papillomavirus E5 Protein Requires a Juxtamembrane Negative Charge for Activation of the Platelet-Derived Growth Factor β Receptor and Transformation of C127 Cells

The bovine papillomavirus E5 gene encodes a 44-amino-acid, homodimeric transmembrane protein that is the smallest known transforming protein. The E5 protein transforms cultured fibroblasts by forming a stable complex with the endogenous platelet-derived growth factor (PDGF) β receptor through transm...

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Pubblicato in:	J Virol
Autori principali:	Klein, Ophir, Kegler-Ebo, Deena, Su, Jennifer, Smith, Steven, DiMaio, Daniel
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Transformation and Oncogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074180/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.3264-3272.1999
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