Intranasal Delivery of Recombinant Parvovirus-Like Particles Elicits Cytotoxic T-Cell and Neutralizing Antibody Responses

We previously demonstrated that chimeric porcine parvovirus-like particles (PPV:VLP) carrying heterologous epitopes, when injected intraperitoneally into mice without adjuvant, activate strong CD4(+) and CD8(+) T-cell responses specific for the foreign epitopes. In the present study, we investigated...

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Detalhes bibliográficos
Main Authors: Sedlik, C., Dridi, A., Deriaud, E., Saron, M. F., Rueda, P., Sarraseca, J., Casal, J. I., Leclerc, C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104030/
https://ncbi.nlm.nih.gov/pubmed/10074120
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