The Transmembrane Domain of Hepatitis C Virus Glycoprotein E1 Is a Signal for Static Retention in the Endoplasmic Reticulum

Hepatitis C virus (HCV) glycoproteins E1 and E2 assemble to form a noncovalent heterodimer which, in the cell, accumulates in the endoplasmic reticulum (ER). Contrary to what is observed for proteins with a KDEL or a KKXX ER-targeting signal, the ER localization of the HCV glycoprotein complex is du...

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Main Authors: Cocquerel, Laurence, Duvet, Sandrine, Meunier, Jean-Christophe, Pillez, André, Cacan, René, Wychowski, Czeslaw, Dubuisson, Jean
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 1999
Ábhair:
Virus-Cell Interactions
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC104019/
https://ncbi.nlm.nih.gov/pubmed/10074109
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