The Transmembrane Domain of Hepatitis C Virus Glycoprotein E1 Is a Signal for Static Retention in the Endoplasmic Reticulum

Hepatitis C virus (HCV) glycoproteins E1 and E2 assemble to form a noncovalent heterodimer which, in the cell, accumulates in the endoplasmic reticulum (ER). Contrary to what is observed for proteins with a KDEL or a KKXX ER-targeting signal, the ER localization of the HCV glycoprotein complex is du...

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Pubblicato in:	J Virol
Autori principali:	Cocquerel, Laurence, Duvet, Sandrine, Meunier, Jean-Christophe, Pillez, André, Cacan, René, Wychowski, Czeslaw, Dubuisson, Jean
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074109/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.2641-2649.1999
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