Effect of Mutations in the Second Extracellular Loop of CXCR4 on Its Utilization by Human and Feline Immunodeficiency Viruses

CCR5 and CXCR4 are the principal CD4-associated coreceptors used by human immunodeficiency virus type 1 (HIV-1). CXCR4 is also a receptor for the feline immunodeficiency virus (FIV). The rat CXCR4 cannot mediate infection by HIV-1(NDK) or by FIV(PET) (both cell line-adapted strains) because of seque...

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Bibliographische Detailangaben
Hauptverfasser: Brelot, Anne, Heveker, Nikolaus, Adema, Karen, Hosie, Margaret J., Willett, Brian, Alizon, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC104012/
https://ncbi.nlm.nih.gov/pubmed/10074102
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