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Double-Stranded Linear Duck Hepatitis B Virus (DHBV) Stably Integrates at a Higher Frequency than Wild-Type DHBV in LMH Chicken Hepatoma Cells

Integration of hepadnavirus DNAs into host chromosomes can have oncogenic consequences. Analysis of host-viral DNA junctions of DHBV identified the terminally duplicated r region of the viral genome as a hotspot for integration. Since the r region is present on the 5′ and 3′ ends of double-stranded...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Gong, Shih S., Jensen, Anne D., Chang, C. J., Rogler, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103974/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882355/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1492-1502.1999
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