Mechanism of Suppression of Hepatitis B Virus Precore RNA Transcription by a Frequent Double Mutation

A double mutation which converts nucleotide 1765 from A to T and nucleotide 1767 from G to A is frequently found in the hepatitis B virus (HBV) genome isolated from HBV patients with chronic hepatitis symptoms. This double mutation is located in the core promoter that controls the transcription of t...

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Pubblicato in:	J Virol
Autori principali:	Li, Jie, Buckwold, Victor E., Hon, Man-wai, Ou, Jing-hsiung
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Replication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882327/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1239-1244.1999
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