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A Phylogenetically Conserved Stem-Loop Structure at the 5′ Border of the Internal Ribosome Entry Site of Hepatitis C Virus Is Required for Cap-Independent Viral Translation

Hepatitis C virus (HCV) initiates translation of its polyprotein under the control of an internal ribosome entry site (IRES) that comprises most of the 341-nucleotide (nt) 5′ nontranslated RNA (5′NTR). A comparative analysis of related flaviviral sequences suggested that an RNA segment for which sec...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Honda, Masao, Beard, Michael R., Ping, Li-Hua, Lemon, Stanley M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103937/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882318/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1165-1174.1999
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