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Non-Antigen-Specific B-Cell Activation following Murine Gammaherpesvirus Infection Is CD4 Independent In Vitro but CD4 Dependent In Vivo

The murine gammaherpesvirus MHV-68 multiplies in the respiratory epithelium after intranasal inoculation, then spreads to infect B cells in lymphoid germinal centers. Exposing B cells to MHV-68 in vitro caused an increase in cell size, up-regulation of the CD69 activation marker, and immunoglobulin...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Stevenson, Philip G., Doherty, Peter C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103927/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882308/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1075-1079.1999
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