Efficient Transduction by an Amphotropic Retrovirus Vector Is Dependent on High-Level Expression of the Cell Surface Virus Receptor

Transduction by murine leukemia virus-based retrovirus vectors is limited in certain cell types, particularly in nondividing cells. But transduction can be inefficient even in cells that divide rapidly. For example, exposure of 208F rat embryo fibroblasts to an excess of an amphotropic retrovirus ve...

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Publié dans:	J Virol
Auteurs principaux:	Kurre, Peter, Kiem, Hans-Peter, Morris, Julia, Heyward, Scott, Battini, Jean-Luc, Miller, A. Dusty
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1999
Sujets:	Gene Therapy
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103856/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9847355/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.1.495-500.1999
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