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Functional Coupling between Replication and Packaging of Poliovirus Replicon RNA

Poliovirus RNA genomes that contained deletions in the capsid-coding regions were synthesized in monkey kidney cells that constitutively expressed T7 RNA polymerase. These replication-competent subgenomic RNAs, or replicons (G. Kaplan and V. R. Racaniello, J. Virol. 62:1687–1696, 1988), were encapsi...

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Autores principales: Nugent, Constance I., Johnson, Kyle L., Sarnow, Peter, Kirkegaard, Karla
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC103849/
https://ncbi.nlm.nih.gov/pubmed/9847348
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