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Processing of the Human Coronavirus 229E Replicase Polyproteins by the Virus-Encoded 3C-Like Proteinase: Identification of Proteolytic Products and Cleavage Sites Common to pp1a and pp1ab

Replicase gene expression by the human coronavirus 229E involves the synthesis of two large polyproteins, pp1a and pp1ab. Experimental evidence suggests that these precursor molecules are subject to extensive proteolytic processing. In this study, we show that a chymotrypsin-like enzyme, the virus-e...

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Pubblicato in:J Virol
Autori principali: Ziebuhr, John, Siddell, Stuart G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103821/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9847320/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.1.177-185.1999
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