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Gamma Interferon Treatment of Patients with Chronic Granulomatous Disease Is Associated with Augmented Production of Nitric Oxide by Polymorphonuclear Neutrophils

Treatment with gamma-interferon (IFN-γ) is associated with reduced frequency and severity of infections in chronic granulomatous disease (CGD), but the mechanism is unknown. Since the inducible nitric oxide (NO) synthase can be amplified by IFN-γ in murine macrophages, for example, we hypothesized t...

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Hlavní autoři: Åhlin, Anders, Lärfars, Gerd, Elinder, Göran, Palmblad, Jan, Gyllenhammar, Hans
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC103734/
https://ncbi.nlm.nih.gov/pubmed/10225847
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