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Marked Suppression of T Cells by a Benzothiophene Derivative in Patients with Human T-Lymphotropic Virus Type I-Associated Myelopathy/Tropical Spastic Paraparesis

In a search for new anti-autoimmune agents that selectively suppress activation of autoreactive T cells, one such agent, 5-methyl-3-(1-methylethoxy)benzo[b]thiophene-2-carboxamide (CI-959-A), was found to be effective. This compound, which is known to suppress tumor necrosis factor alpha (TNF-α)-ind...

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Detalhes bibliográficos
Main Authors: Makino, Masahiko, Azuma, Miyuki, Wakamatsu, Shin-Ichi, Suruga, Yukio, Izumo, Shuji, Yokoyama, Mitchel M., Baba, Masanori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC103716/
https://ncbi.nlm.nih.gov/pubmed/10225829
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