Negative Control of Flagellum Synthesis in Pseudomonas aeruginosa Is Modulated by the Alternative Sigma Factor AlgT (AlgU)

Many respiratory isolates of Pseudomonas aeruginosa from cystic fibrosis patients are mucoid (alginate producing) yet lack flagella. It was hypothesized that an alginate regulator inhibits flagellar gene expression. Mutations in algB, algR, and algT resulted in nonmucoid derivatives, yet algT mutant...

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Bibliographic Details
Main Authors: Garrett, Edward S., Perlegas, Demetra, Wozniak, Daniel J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC103708/
https://ncbi.nlm.nih.gov/pubmed/10572149
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