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Roles of Three Histidine Kinase Genes in Hyphal Development and Virulence of the Pathogenic Fungus Candida albicans

The pathogenic fungus Candida albicans harbors three histidine kinase genes called CaSLN1, CaNIK1, and CaHK1. The disruption of any one of these three genes impaired the hyphal formation and attenuated the virulence of C. albicans in a mouse systemic candidiasis model. The effects of the disruption...

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Detalhes bibliográficos
Main Authors: Yamada-Okabe, Toshiko, Mio, Toshiyuki, Ono, Naomi, Kashima, Yuji, Matsui, Mitsuaki, Arisawa, Mikio, Yamada-Okabe, Hisafumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC103686/
https://ncbi.nlm.nih.gov/pubmed/10572127
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