2, 4-Diamino-6- hydroxy pyrimidine inhibits NSAIDs induced nitrosyl-complex EPR signals and ulcer in rat jejunum

BACKGROUND: It has been suggested that one aspect of non-steroidal anti-inflammatory drugs induced intestinal damage is due to either uncoupling of mitochondrial oxidative phosphorylation or inhibition of electron transport. We investigated the latter possibility using electron paramagnetic resonanc...

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Detalhes bibliográficos
Main Authors: Somasundaram, S, Simpson, R, Rafi, S, Shergill, JK, Bjarnason, I, Wrigglesworth, J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC103670/
https://ncbi.nlm.nih.gov/pubmed/11960558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-2-8
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