Mutational Analysis of the RecJ Exonuclease of Escherichia coli: Identification of Phosphoesterase Motifs

The recJ gene, identified in Escherichia coli, encodes a Mg(+2)-dependent 5′-to-3′ exonuclease with high specificity for single-strand DNA. Genetic and biochemical experiments implicate RecJ exonuclease in homologous recombination, base excision, and methyl-directed mismatch repair. Genes encoding p...

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Bibliographic Details
Main Authors: Sutera, Vincent A., Han, Eugene S., Rajman, Luis A., Lovett, Susan T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Enzymes and Proteins
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC103638/
https://ncbi.nlm.nih.gov/pubmed/10498723
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