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Alteration of the Repressor Activity of MarR, the Negative Regulator of the Escherichia coli marRAB Locus, by Multiple Chemicals In Vitro

MarR negatively regulates expression of the multiple antibiotic resistance operon (marRAB) in Escherichia coli. In this study, it was demonstrated that sodium salicylate, plumbagin, 2,4-dinitrophenol, and menadione–inducers of the marRAB operon in whole cells–all interfered with the repressor activi...

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Autors principals: Alekshun, Michael N., Levy, Stuart B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC103602/
https://ncbi.nlm.nih.gov/pubmed/10419969
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