Mutations That Extend the Specificity of the Endonuclease Activity of λ Terminase

Terminase, an enzyme encoded by the Nu1 and A genes of bacteriophage lambda, is crucial for packaging concatemeric DNA into virions. cosN, a 22-bp segment, is the site on the virus chromosome where terminase introduces staggered nicks to cut the concatemer to generate unit-length virion chromosomes....

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Main Authors: Arens, Jean Sippy, Hang, Qi, Hwang, Young, Tuma, Bill, Max, Sara, Feiss, Mike
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1999
主題:
Bacteriophages
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC103552/
https://ncbi.nlm.nih.gov/pubmed/9864333
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